Exit the airport to the right and go in the direction of San Ramon, Jacó , Quepos. Take the first turn right following a sign for Poas Volcano / Alajuela.
Follow signs to San Ramon, take the exit for Jacó / Quepos / Manuel Antonio, turn left at the stop sign (there is a brown sign for Parque Nacional Manuel Antonio).
Next up is Atenas — a small town with a gas station and other amenities.
In San Mateo, follow the signs for Punta Leona / Jacó .
Go straight through the next town of Orotina, take the exit to the right, the sign says Jacó , Quepos, Caldera.
Then follow the signs for Jacó / Quepos.
Next, you will cross over the Tarcoles river bridge, park either before or after the bridge, walk over the bridge to get a great view of many wild crocodiles.
Follow the signs to Jacó and enter the third entrance to town on the right hand side.